Estimates of HIV incidence rates among high-risk heterosexuals (HRH) in the United States have been limited to heterosexual subgroups like prison inmates and commercial sex workers. In this analysis, we estimate incidence with detuned assay testing among a group of HRH defined through a multidimensional sampling strategy and recruited through respondent-driven sampling. Incidence was 3.31% per year (95% confidence interval = 1.43 to 6.47) overall and 2.59% per year (95% confidence interval = 0.84 to 6.06) among participants with no lifetime history of drug injection or male-to-male sex. This study design is suggested as an efficient method for recruiting HRH for cohort studies and behavioral interventions.
From the *New York City Department of Health and Mental Hygiene, New York, NY; †National Development and Research Institutes, Inc, New York, NY; and ‡New York University, College of Nursing, New York, NY.
Received for publication August 13, 2010; accepted October 15, 2010.
Supported by funding by a cooperative agreement between the New York City Department of Health and Mental Hygiene and the Centers for Disease Control and Prevention (grant #U62/CCU223595-03-1).
The authors have no conflicts of interests to disclose.
Correspondence to: Samuel M. Jenness, MPH, HIV Epidemiology Program, New York City Department of Health and Mental Hygiene, 346 Broadway, Suite 707D, New York, NY 10013 (e-mail: firstname.lastname@example.org).