Welcome 12th Annual International Meeting of the Institute of Human Virology of the University of Maryland School of Medicine

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JAIDS Journal of Acquired Immune Deficiency Syndromes:
doi: 10.1097/01.qai.0000397290.40152.51
Program Information and Acknowledgments
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    By Robert C. Gallo, Founder and Director, Institute of Human Virology and Giovanni Latorre, President, University of Calabria

    Dear colleagues and friends,

    University of Calabria President Giovanni Latorre and I welcome you to the 12th Annual Meeting of the Institute of Human Virology (IHV). For the first time since the meeting began in the mid-1970s at the National Cancer Institute, it is taking place outside the Baltimore/Washington, DC area. The setting for this year's meeting, Tropea, Italy, is one of extraordinary beauty and ancient historical contributions. The region is among the oldest civilization in Europe and includes the location of Pythagorus, Herodotus, and other greats of the ancient world, as well as the land of origin of many famous Greek legends, some told by Homer. Today, Tropea attracts visitors to the Costa degli Dei (Coast of the Gods), one of the most beautiful regions in Italy and food afficionados seeking the famous local red onion that was hailed by the Roman Pliny the Elder for its gastronomic and healing potential. Nearby are the ancient Aeolian islands. Together with Calabria and Sicily, their cultures dating back thousands of years before Christ, also with their many legends.

    It is important that we acknowledge Professor Arnaldo Caruso, of the University of Brescia but who originally hails from Calabria, chair of the Italian Organizing Committee; without his vision and support, this meeting in Calabria would not be possible. Dr. Caruso currently holds an Adjunct Professorship at IHV and the University of Maryland School of Medicine. This collaboration planted the idea for changing the venue of this 12th Annual Meeting. Our meeting has always been a venue for science of AIDS and cancer; this year we bring the meeting to Italy, in part, as a recognition of our many international colleagues and collaborators.

    We would like to thank several organizations who have committed their support while we are still in the early stages of planning this event: the National Cancer Institute and National Institute of Allergy and Infectious Disease of the National Institutes of Health, the Office of AIDS Research, Italian Society for Medical Virology (SIVIM), Medestea, Sanofi-Pasteur, and Sanyo, Inc.. We will be pleased to recognize other supporting partners as the list grows.

    The Annual Meeting has a traditional emphasis on the biology of HIV/AIDS, including the perspectives of basic science, clinical science and new treatment and prevention approaches. In 2010 we are expanding the emphasis on vaccines to recognize the importance of this area and learn how recent successes may guide new directions in HIV vaccine research and development. International vaccine experts will describe vaccine immunogens that are moving through human clinical trials, efforts to define immune correlates of protection, possible applications for therapeutic vaccination and a range of vaccine delivery strategies that are bringing us closer, everyday, to effective protection from HIV disease. Recognizing the important parallels of HIV and cancer, we include discussions of cancer-causing viruses, new cancer vaccines and fundamental research in cancer. In developed countries, cancer is emerging as the leading cause of death for persons with HIV, and these fields are inexorably linked in terms of both science and medicine. We also emphasize the problems of HIV/AIDS in the developing world by inviting experts on the specific impacts of HIV/AIDS on sub-Saharan Africa.

    This year, in keeping with the meeting's focus on vaccines, we are honored to present the IHV Lifetime Achievement Award for Scientific Contributions to Dr. Rino Rappuoli of Novartis Vaccines in Sienna, Italy. Rappuoli, currently the Global Head of Vaccines Research for Novartis Vaccines & Diagnostics (Siena, Italy), was elected as a foreign associate of the National Academy of Sciences in 2005. He spent his career developing vaccines for pertussis, meningitis, and Helicobacter pylori and is jointly responsible for engineering the carrier protein used in many conjugate vaccines. He is credited with launching the field of reverse vaccinology, the first fruits of which are revealed in the special Inaugural Article of the Proceedings of the US National Academy of Sciences, where he describes a universal vaccine for serogroup B meningococcus. Previous recipients of the IHV Lifetime Achievement Award for Scientific Contributions are: Isaac Witz, Maxine Singer, Manfred Eigen, Paul Zamecnik, Jan Svoboda, Alexander Rich, Hilary Koprowski, Maurice Hilleman, and George Klein.

    We will also be presenting the IHV Lifetime Achievement Award for Public Service to Harry Huge, Esq. Harry is a friend of the Institute and was with us at the beginning when the State of Maryland recruited Bob Redfield, Bill Blattner, and Robert Gallo. He is a practicing attorney in Charleston, South Carolina and has enjoyed a long and distinguished law career, serving as an arbitrator on the National Tobacco Arbitration Panel, a Special Master for the U.S. District Court for the District of Columbia; and chairman of the United Mine Workers Health and Retirement Fund. He is currently co-counsel representing family members of the victims of the September 11, 2001 attacks victims and in late 2002, he was appointed co-prosecutor with the Chief German Federal Prosecutor by the German Federal Criminal Court in the trials of Hamburg cell terrorists. Harry was also awarded the Order of the Cross of Terra Mariana from the country of Estonia in 2006, for work by him on behalf of Estonia in the late 1980's and early 1990's when Estonia regained its independence from the Soviet Union in 1991 in a bloodless transition. Huge worked on behalf of Estonia with the U.S. Administration and Congress during this period as well as in Estonia. Harry and his wife, Reba, founded and operate two foundations which award college scholarships to Nebraska high school seniors. Over the past five years, they have awarded 30 scholarships to students who attend colleges and universities in Nebraska, Iowa, Kansas and South Dakota. Prior honorees include: John Evans, Robert Gray, Martin Delaney, and Stewart Greenebaum.

    For the first time, we are presenting an award for teaching excellence. This award, from our Institute and his many students and colleagues, is a “surprise” for Michele La Placa, MD. He has been educating medical students and researchers in the field of microbiology in Italy since 1954. Dr. La Placa is the author of the manual “Principles of Medical Microbiology,” (Esculapio, Bologna, Italy), the most widely used textbook of Microbiology in the medical schools of Italian universities, which is currently in its 12th edition.

    We hope everyone will take the opportunity to visit the town square in Cosenza, the provincial capitol of the Tropea area of Calabria, where large modern sculptures by world famous artists are exhibited and a fountain and the central square honors the Kennedy family. We expect that Ms. Kathleen Kennedy Townsend, former lieutenant governor of Maryland and daughter of U.S. Senator Robert F. Kennedy, who is the Chair of our Board of Advisors will attend.

    We are grateful to those joining us in Tropea this year and are confident that this meeting will write another important chapter in the book of human retrovirology. I also want to acknowledge my co-workers David Pauza and Beth Peterson, whose tireless efforts for this meeting now reach fruition.

    Cordially,

    Robert Gallo, Director and Professor, Institute of Human Virology

    Giovanni Latorre, President, University of Calabria

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    The Institute of Human Virology www.ihv.org

    Mission Statement

    The Institute of Human Virology (IHV) is a world-class center of excellence focusing on chronic viral diseases and virally linked cancers. IHV is dedicated to biomedical research leading to improved treatment and prevention of these diseases.

    Our unique structure connects cohesive, multidisciplinary research and clinical programs so that new treatments are streamlined from discovery to patients. IHV is forging local and international programs for research and treatment of human disease.

    Robert C. Gallo

    Director, Co-Director, Division of Basic Science and Vaccine Research

    William A. Blattner

    Associate Director, Director, Division of Epidemiology and Prevention

    Robert R. Redfield

    Associate Director, Director, Division of Clinical Care and Research

    C. David Pauza

    Associate Director

    George Lewis

    Co-Director, Division of Basic Science and Vaccine Research

    Joseph L. Bryant

    Director, Division of Animal Models

    Dave Wilkins

    Chief Operating Officer

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    Tropea, Calabria, Italy

    We are pleased to announce the IHV Meeting, for the first time in its history, will be held outside the Baltimore/Washington, DC area. The location for the meeting is Tropea, Italy. Tropea, specifically, and its region, Calabria, are a well-kept secret by American standards, and those who join us are in for a special treat.

    Located on the western tip of the Italian peninsula on the Tyrrhenian Sea, the coastline is affectionately known as the “Costa degli Dei,” or the “Coast of the Gods.” Tropea is a very popular vacation destination among Italians and other Europeans. It is best known for stunning beaches, medieval architecture, and the Tropea Red Onion. However, the entire region of Calabria is of great historical interest, a region which was among the first to develop what we call civilization in the Western world.

    IHV is very fortunate for the opportunity to share hosting honors with the University of Calabria and the Italian Society for Medical Virology. We all hope that you will join us for what will surely be a special experience.

    Sunshine Club Hotel

    White chest snc Loc

    89866 Ricadi (vv)

    Booking and Information Office

    Tel + 39 0963 66 57 13

    Fax + 39 0963 1930 362

    E-mail: info@sunshinehotel.it

    http://www.sunshinehotel.it

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    Board of Advisors

    Kathleen Kennedy Townsend

    Chairperson

    Former Lieutenant Governor of Maryland, Baltimore, Maryland

    Fred Cannon

    Senior Vice President for Government

    Relations, BMI, Inc.

    New York, NY

    Robert Charrow

    Greenberg Traurig LLP

    Washington, DC

    John P. Coale

    Washington, DC

    Janet Langhart Cohen

    Chevy Chase, MD

    Barbara J. Culliton

    Science Journalist and Policy Consultant

    Washington, D.C.

    Elijah Cummings

    United States House of Representatives

    Baltimore, Maryland

    John Evans

    Evans Telecommunications

    Key West, Florida

    Arthur Gajarsa

    United States Court of Appeals for the Federal Circuit, Washington, DC

    Robert Gray

    Chairman,Gray and Company II

    Miami Beach, Florida

    William Hall

    University College Dublin

    Dublin, Ireland

    William A. Haseltine

    Haseltine Foundation for Medical

    Sciences and the Arts

    Washington, DC

    Ernest F. Hollings

    Medical University of South Carolina

    Charleston, SC

    Richard E. Hug

    HUG ENTERPRISES, INC.

    Baltimore, MD

    Toshiaki Inoue

    Sanyo E&E America Company

    Bensenville, IL

    Mark Kaplan

    University of Michigan

    Ann Arbor, Michigan

    Sheila Kast

    WYPR Radio

    College Park, MD

    Nancy Kopp

    State Treasurer, Maryland State

    Government

    Annapolis, Maryland

    Hilary Koprowski

    Thomas Jefferson University

    Philadelphia, PA

    Thomas Lynch

    Amarin Pharmaceutical, Ltd.

    Dublin, Ireland

    HRH Princess Chulabhorn

    Mahidol

    Mahidol University

    Bangkok, Thailand

    Timothy Moynahan

    Moynahan & Minnella, LLC

    Waterbury, Connecticut

    Franco Nuschese

    Georgetown Entertainment Group

    Washington, DC

    Thomas Paese, Esquire

    Buchanan Ingersoll and Rooney

    Harrisburg, Pennsylvania

    Chris Y H Tan

    Asian Institute of Molecular and Cell Biology

    Vancouver, British Columbia

    Jeffrey B. Trammell

    Trammell and Company

    Washington, D.C.

    Lenny Wilkens

    National Basketball Association

    Hall of Fame Coach and Player

    Medina, Washington

    James Wyngaarden

    Former Director, National Insitutes of Health

    Durham, North Carolina

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    Ex-Officio Members

    Robert C. Gallo

    Director, Institute of Human Virology

    William E. Kirwan

    Chancellor

    University System of Maryland

    E. Albert Reece

    Dean

    University of Maryland School of Medicine

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    Scientific Advisory Board

    Hilary Koprowski, M.D.

    Chair

    Thomas Jefferson University

    Philadelphia, Pennsylvania

    Edward A. Berger, Ph. D.

    National Institutes of Health

    Bethesda, Maryland

    Farley Cleghorn, M.D.

    Constella Group

    Washington, DC

    Myron S. Cohen, M.D.

    University of North Carolina School of Medicine

    Chapel Hill, North Carolina

    Max Essex, D.V.M., Ph.D.

    Harvard School of Public Health

    Cambridge, Massachusetts

    Warner Greene, M.D., Ph.D.

    Gladstone Institute of Virology and Immunology

    San Francisco, California

    Mark Kaplan, M.D., FACP

    University of Michigan

    Medical Center

    Ann Arbor, Michigan

    Michel Klein, Ph.D.

    Canadian Network for Vaccines

    and Immunotherapeutics

    Toronto, Canada

    Myron Levine, M.D., D.T.P.H.

    University of Maryland

    School of Medicine

    Baltimore, Maryland

    Erling C. J. Norrby, M.D., Ph.D.

    The Royal Swedish Academy

    of Sciences

    Stockholm, Sweden

    Joseph Pagano, M.D.

    University of North Carolina School of Medicine

    Chapel Hill, North Carolina

    Kathleen Squires, MD

    Thomas Jefferson University

    Philadelphia, Pennsylvania

    Mario Stevenson, Ph.D.

    University of Massachusetts Medical School

    Worcester, Massachusetts

    Sten Vermund, M.D., Ph.D.

    Vanderbilt University Institute for Global Health

    Nashville, Tennessee

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    International Organizing Committee

    The Institute of Human Virology of the University of Maryland School of Medicine is very grateful for the assistance provided by our International Organizing Committee.

    Alan Bernstein

    Global HIV Vaccine Enterprise, New York, NY, USA

    Gunnel Biberfeld

    Karolinska Institute, Stockholm, Sweden

    Arnaldo Caruso

    University of Brescia, Brescia, Italy

    Carl Dieffenbach

    National Institutes of Health, Bethesda, MD, USA

    Jose Esparza

    Bill and Melinda Gates Foundation, Seattle, WA, USA

    K.T. Jeang

    National Institutes of Health, Bethesda, MD, USA

    Reinhard Kurth

    Robert-Koch Institutes, Berlin, Germany

    Alain Lafeuillade

    General Hospital, Toulon, France

    Adriano Lazzarin

    Fondazione San Raffaele del Monte Tabor, Milan, Italy

    C. David Pauza

    Institute of Human Virology, Baltimore, MD, USA

    Guido Poli

    Fondazione San Raffaele del Monte Tabor, Milan, Italy

    Rino Rappuoli

    Novartis, Siena, Italy

    Mario Stevenson

    University of Massachusetts, Worcester, MA, USA

    Umberto Tirelli

    National Cancer Institute, Aviano, Pordenone, Italy

    Isaac Witz

    Tel Aviv University, Tel Aviv, Israel

    Robert Yarchoan

    National Cancer Institute, Bethesda, MD, USA

    Yi Zeng

    Chinese Center for Disease Control, Beijing, China

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    Special Acknowledgements

    The Institute of Human Virology of the University of Maryland and the University of Calabria would like to thank the following organizations. Without their continued and generous support, this meeting would not be possible.

    Benefactor

    Italian Society for Medical Virology – SIVIM

    Medestea

    National Institutes of Health

    National Institute of Allergy and Infectious Diseases

    Office of AIDS Research

    Underwriter

    US Military HIV Research Program (MHRP)

    The Fondazione Bonino Pulejo

    Supporters

    Abbott Molecular Diagnostics, Inc.

    Gilead, Inc.

    National Cancer Institute

    Contributors

    Epiphany Biosciences, Inc.

    Sergio Mazzuca, Scintille Jewelry

    MinXray, Inc.

    Partec Italy

    Profectus Biosciences, Inc.

    Sanofi-Pasteur

    Sanyo, Inc.

    Sysmex GmbH

    University of Calabria

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    2010 IHV Lifetime Achievement Award for Scientific Contributions Rino Rappuoli, Ph.D.

    This year, in keeping with the meeting's focus on vaccines, we are honored to present the IHV Lifetime Achievement Award for Scientific Contributions to Dr. Rino Rappuoli of Novartis Vaccines in Sienna, Italy. Rappuoli, currently the Global Head of Vaccines Research for Novartis Vaccines & Diagnostics (Siena, Italy), was elected as a foreign associate of the National Academy of Sciences in 2005. He is considered one of the major world experts in R&D of vaccines. In fact, Rino Rappuoli has developed the first recombinant bacterial vaccine (against pertussis) and a conjugate vaccine against meningococcus C. Both products have been approved for human use. Currently, he is involved in the development of a vaccine against group B meningococcus using a genome-based approach, which has been termed reverse vaccinology, in the development of influenza vaccines produced in cell culture, and the development of vaccines against avian influenza. He is co-founder of the field of cellular microbiology, a discipline that has merged cell biology and microbiology.

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    2010 IHV Lifetime Achievement Award for Public service Harry Huge

    We will also be presenting the IHV Lifetime Achievement Award for Public Service to Harry Huge, Esq. Harry is a friend of the Institute and was with us at the beginning when the State of Maryland recruited Bob Redfield, Bill Blattner, and me. He is a practicing attorney in Charleston, South Carolina, and Washington, DC, and has enjoyed a long and distinguished law career, serving as an arbitrator on the National Tobacco Arbitration Panel, a Special Master for the U.S. District Court for the District of Columbia; and chairman of the United Mine Workers Health and Retirement Fund. He is currently co-counsel representing family members of the victims of the September 11, 2001 attacks and in late 2002, he was appointed co-prosecutor with the Chief German Federal Prosecutor by the German Federal Criminal Court in the trials of Hamburg cell terrorists. Harry was also awarded the Order of the Cross of Terra Mariana from the country of Estonia in 2006, for work by him on behalf of Estonia in the late 1980's and early 1990's when Estonia regained its independence from the Soviet Union in 1991 in a bloodless transition. Huge worked on behalf of Estonia with the U.S. Administration and Congress during this period as well as in Estonia. Harry and his wife, Reba, founded and operate two foundations which award college scholarships to Nebraska high school seniors. Over the past five years, they have awarded 30 scholarships to students who attend colleges and universities in Nebraska, Iowa, Kansas and South Dakota.

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    2010 IHV Lifetime Achievement Award for Public Service Michele LaPlaca, M.D.

    For the first time, we are presenting an award for teaching excellence. Michele La Placa, MD has been educating medical students and researchers in the field of microbiology since 1954. Dr. La Placa's academic career began as a Lecturer in Microbiology at the Medical School of the University of Bologna, November 1, 1954. He is the author of the manual “Principles of Medical Microbiology,” (Esculapio, Bologna, Italy), the most widely used textbook of microbiology in the medical schools of Italian universities, which is currently in its 12th edition. Dr. LaPlaca's students, many of whom are now leaders in their own right, say “…he was an excellent teacher: able to involve and captivate students and colleagues in an enrapturing way, since he always believed in the importance of microbiology, spending his days studying before teaching.”

    His colorful career was characterized by intensive laboratory research in all fields of microbiology and virology, and he spent many years working on HIV pathogenesis with great success. The link between progenitor cells and Tat/gp120 drew his attention and prompted him to create a group for intensive study of this topic. We have not enough time to describe his value. We can only say - Thank you, Michele.

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    Previous Recipients of Lifetime Achievement Awards

    Scientific Contributions

    1999 George Klein, Karolinska Institute, Stockholm, Sweden

    2000 Maurice Hilleman, Merck Research Laboratories, Sumneytown, Pennsylvania

    2001 Hilary Koprowski, Thomas Jefferson University, Philadelphia, Pennsylvania

    2002 Alexander Rich, Massachusetts Institute of Technology, Cambridge, Massachusetts

    2003 Jan Svoboda, Institute of Molecular Genetics, Prague, Czech Republic

    2004 Paul Zamecnik, Massachusetts General Hospital, Boston, Massachusetts

    2005 Manfred Eigen, Max Planck Institute, Göttingen, Germany

    2006 Maxine Singer, National Institutes of Health, Bethesda, Maryland

    2008 Isaac P. Witz, Tel Aviv University, Tel Aviv, Israel

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    Public Service

    2004 Stewart Greenebaum, Greenebaum and Rose Associates, Inc., Baltimore, Maryland

    2006 Martin Delaney, Project Inform, San Francisco, California

    2008 John D. Evans, Evans Telecommunication Company and The Honorable Robert K. Gray, Gray and Company II, Miami, FL

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    Mark Your Calendar!

    13th Annual International Meeting of the Institute of Human Virology

    Marriott Waterfront Hotel Baltimore, MD

    October 30 - November 2, 2011

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    Evening Events Schedule

    Monday, October 4, 2010

    6 p.m. Welcome Reception and Dinner

    Location: Sunshine Club Hotel Ballroom

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    Tuesday, October 5, 2010

    6 - 7:30 p.m. Aperitivo

    8:30 p.m. Lifetime Achievement Gala Banquet and Awards Ceremony

    Location: Sunshine Club Hotel Ballroom

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    Wednesday, October 6, 2010

    6 - 7:30 p.m. Aperitivo

    8:30 p.m. Historical Lecture with Regional Dance Performances

    Location: Sunshine Club Hotel Ballroom

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    Thursday, October 7, 2010

    Scintille Jewelry Fashion Event - By Invitation Only

    No other events scheduled

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    Friday, October 8, 2010

    7:30 p.m. Evening Boat Ride to Stromboli

    At participants' expense

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