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JAIDS Journal of Acquired Immune Deficiency Syndromes:
doi: 10.1097/QAI.0000000000000220
Brief Report: Clinical Science

The Montreal Cognitive Assessment to Screen for Cognitive Impairment in HIV Patients Older Than 60 Years

Milanini, Benedetta Psy*; Wendelken, Lauren A. MS; Esmaeili-Firidouni, Pardis BS; Chartier, Maggie PsyD, MPH; Crouch, Pierre-Cedric NP, RN§; Valcour, Victor MD, PhD†,‖

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Abstract

Abstract: Progress in HIV treatments has led to HIV-infected patients living into their 60s and older. Because HIV-associated neurocognitive disorder (HAND) in older age is associated with more executive dysfunction, cognitive screening instruments tapping this domain may be optimal. We examined the Montreal Cognitive Assessment to identify HAND in 67 HIV-infected patients older than 60 years, of which 40% were diagnosed with HAND. Receiver operating characteristic curve identified an optimal cutpoint of ≤ 25 for HAND with a sensitivity of 72% and specificity of 67%. We conclude that the Montreal Cognitive Assessment has only moderate performance characteristics for cognitive screening of HIV-infected elders.

© 2014 by Lippincott Williams & Wilkins

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