AIDSRelief, a consortium of Catholic Relief Services, the Institute of Human Virology (IHV), Catholic Medical Mission Board, Interchurch Medical Assistance, and Futures Group was formed in 2004 to respond to the President's Emergency Plan for AIDS Relief(PEPFAR) Track 1.0 Care and Treatment Program. Since that time, the AIDSRelief consortium has delivered HIV care to 706,953 patients, initiated antiretroviral treatment in 395,088 patients, and still had 268,631 patients on treatment at the transition quarter, in 10 countries. Over this time frame, much has been learned about the provision of care in resource constrained settings. Keys to the success of this program have been the continuous evaluation of treatment sites, the revision of programs with lower than expected outcomes, and the promotion of successful strategies throughout the program. The success of antiretroviral treatment in these settings is dependent on the durability of the initial regimen. Important factors contributing the durability of the initial regimen include; choice of the initial regimen, treatment strategy, and care delivery system. With appropriate regimen choice, treatment strategy and care delivery system, successful delivery of antiretroviral treatment is possible in even the most rural setting. Continued investment in health care infrastructure and care delivery systems is essential to maintain and expand the successes of the past 8 years.
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