Oral PrEP with TDF-FTC has been shown to reduce HIV transmission by approximately 40 % in MSM and 76% in serodiscordant couples. HPTN 052 study also recently demonstrated that providing early antiretroviral treatment to HIV positive individuals reduced transmission of the virus to their partners. Nigeria has a generalized epidemic with some states having high rates of transmission where young people are at high risk. In addition, reports from antenatal clinics show high rates of serodiscordant couples in the central and southern parts of the country. Nigeria is aggressively pursuing innovative behavioral and biomedical interventions to reduce HIV transmission. The planned expansion of prevention programs in Nigeria could offer unique opportunities to introduce PrEP for young women and/or serodiscorant couples and treatment as prevention for some targeted populations. The introduction of these new prevention technologies as part of combination prevention could be important contributions to Nigeria's efforts to rapidly and significantly reduce the incidence of HIV transmission.
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