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Is Total Community Viral Load a Robust Predictive Marker of the Efficacy of the TasP Strategy?

Henard, Sandrine MD*; Jeanmaire, Eliette MD*; Nguyen, Yohan MD; Yazdanpanah, Yazdan MD, PhD; Cheret, Antoine MD; Hoen, Bruno MD, PhD§; Rey, David MD; Borel, Alice MD; Chavanet, Pascal MD, PhD#; May, Thierry MD, PhD*; Rabaud, Christian MD, PhD*For The ICONE Group

JAIDS Journal of Acquired Immune Deficiency Syndromes: November 1st, 2012 - Volume 61 - Issue 3 - p 400–402
doi: 10.1097/QAI.0b013e318263a111
Brief Report: Epidemiology and Prevention

Abstract: A mild but significant association between a decrease in the total community viral load (CVL) and a decrease in the number of new HIV diagnoses was observed between 2005 and 2010 in the population of northern and eastern France. This result suggests that CVL could be used as robust marker of the efficacy of the “Treatment as Prevention” strategy, and it may even be stronger if a large number of undiagnosed patients and early HIV infection cases indicated by extend screening are included in the CVL measurement.

*Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Nancy, Nancy, France

Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Reims, Reims, France

Service des maladies infectieuses et tropicales, Centre Hospitalier de Tourcoing, Tourcoing, France

§Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Besançon, Besançon, France

Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France

Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire d'Amiens, Amiens, France

#Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Dijon, Dijon, France.

Correspondence to: Sandrine Henard, MD, Service de maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Nancy, 9 allée du Morvan, 54500 Vandœuvre-lès-nancy, France (e-mail: sandrine.henard@wanadoo.fr).

The authors have no funding or conflicts of interest to disclose.

Received February 27, 2012

Accepted May 30, 2012

© 2012 Lippincott Williams & Wilkins, Inc.