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Efficacy of Brief Interventions in Clinical Care Settings for Persons Living With HIV

Lightfoot, Marguerita PhD*; Rotheram-Borus, Mary Jane PhD; Comulada, W Scott DrPH; Reddy, Vanessa S MS; Duan, Naihua PhD§

JAIDS Journal of Acquired Immune Deficiency Syndromes: March 1st, 2010 - Volume 53 - Issue 3 - p 348-356
doi: 10.1097/QAI.0b013e3181c429b3
Clinical Science

Prevention of HIV transmission from patients living with HIV (PLH) is a high national priority and strategies that are easy to implement and sustain to eliminate sexual transmission acts among PLH are needed. We evaluated a brief intervention that focused primarily on the enhancing motivations and encouraging PLH to act in accordance with their values without providing the intensity of the existing evidence-based programs for PLH. Using a quasiexperimental design, six medical clinics in Los Angeles County, CA, were evaluated across three intervention conditions: 1) computerized delivery; 2) provider delivery; or 3) standard care. We examined longitudinal changes in patients' reports of the number of HIV-negative (HIV-) or serostatus-unknown sexual partners and the number of unprotected vaginal and anal sex acts. Among 566 PLH, PLH in the computerized delivery condition reported a significant decrease in the number of HIV-/unknown sexual partners compared with the provider delivery and standard care conditions and a significant decrease in the number of unprotected sex acts in comparison to the standard care condition. Computerized motivational interventions delivered in waiting rooms at medical clinics may be an efficient strategy to reduce unprotected sex acts among PLH.

From the *University of California, San Francisco, CA; †Center for Community Health, University of California, Los Angeles, CA; ‡The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Hanover, NH; and §Department of Biostatistics and Psychiatry at Columbia University, New York, NY.

Received for publication March 27, 2009; accepted September 30, 2009.

Supported by a grant to the UCLA California AIDS Research Center from the University-wide AIDS Research Program (CC02-LA-001).

Correspondence to: Marguerita Lightfoot, PhD, Associate Professor of Medicine, Co-Director, Center for AIDS Prevention Studies (CAPS), 50 Beale Street, Suite 1300, San Francisco, CA 94105 (e-mail:

© 2010 Lippincott Williams & Wilkins, Inc.