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JAIDS Journal of Acquired Immune Deficiency Syndromes:
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Reanalysis of the HIV-1 Circulating Recombinant Form A/E (CRF01_AE): Evidence of A/E/G Recombination.

Magiorkinis, Gkikas; Paraskevis, Dimitris; Magiorkinis, Emmanouil; Vandamme, Anne-Mieke; Hatzakis, Angelos

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Abstract

: Circulating recombinant form (CRF) 01_AE caused an extensive HIV-1 epidemic in Thailand and Southeast Asia. Reanalysis of the recombination pattern of CRF01_AE suggested a more complicated pattern of mosaicism consisting of subtypes A, G, and E. These findings provide evidence that CRF01_AE originated from recombination between at least three different subtypes.

(C) 2002 Lippincott Williams & Wilkins, Inc.

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