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Trends in Antiretroviral Therapy and Mother-Infant Transmission of HIV

Cooper Ellen R.; Charurat, Manhattan; Burns, David N.; Blattner, William; Hoff, Rodney; for The Women and Infants Transmission Study Group
JAIDS Journal of Acquired Immune Deficiency Syndromes: May 1st, 2000
Brief Report: PDF Only

Summary:Trends in the vertical transmission rate of HIV and evolving antiretroviral usage between 1990 and 1998 within the Women and Infants Transmission Study were evaluated. A decline in mother-infant transmission was temporally associated with advances in therapy, especially when regimens including a protease inhibitor were included in the analysis.

Address correspondence and reprint requests to Ellen R. Cooper, Pediatric AIDS Program. Boston Medical Center, 774 Albany Street, 5th Floor, Boston, MA 02118-2393, U.S.A.

Manuscript received December 13, 1999; accepted February 16, 2000.

© 2000 Lippincott Williams & Wilkins, Inc.