Vitamin A Deficiency in Non-Vitamin-Supplemented Patients with AIDS: A Cross-Sectional Study.

Karter, Dennis L.; Karter, Andrew J.; Yarrish, Robert; Patterson, Claire; Kass, Philip H.; Nord, Jill; Kislak, Jay Ward
Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology: February 1995
ORIGINAL ARTICLE: PDF Only

Summary: The prevalence of vitamin A deficiency and its association with dietary retinol intake in patients with AIDS was assessed in a cross-sectional study. Sixty eligible patients with AIDS provided serum samples that were analyzed for retinol content. Exclusion criteria included current use of vitamin supplements (57% of the 140 willing to participate) and pregnancy (none). Past dietary intake was determined using a standardized food intake frequency questionnaire. The prevalence of hyporetinemia was 22%. This was a 241-fold greater prevalence than that of a representative sample of the U.S. population, after adjusting for age and sex. There was a positive association between serum retinol status and dietary intake, but 27% of those with adequate intake had serum retinol levels below the normal range. These findings suggest that regardless of intake, patients with AIDS may represent a population at considerable risk of vitamin A deficiency.

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