Evaluation and management of patients with nocturiaEasterling, S. Adair PA-C; Master, Viraj MD; Carney, K. Jeff MD, PharmDJournal of the American Academy of Physician Assistants: February 2014 - Volume 27 - Issue 2 - p 36–42 doi: 10.1097/01.JAA.0000442703.33717.85 Review Article Abstract Author Information ABSTRACT: Nocturia, or awakening one or more times to void at night, becomes clinically significant with two or more voids a night. In the past, nocturia has typically been viewed as a symptom of benign prostatic hyperplasia and/or overactive bladder syndrome. However, newer evidence supports that this is no longer just a symptom but a medical condition that warrants further workup and treatment given its effect on quality of life. The negative effects of nocturia include sleep fragmentation, decreased productivity at work, and increased risk of falls and fractures. A workup to find the underlying cause of nocturia will help guide treatment, which may include pharmacologic agents. S. Adair Easterling practices at Grady Memorial Hospital in Atlanta, Ga. Viraj Master is an associate professor of urology and director of clinical research in the Department of Urology at Emory University School of Medicine in Atlanta, Ga., and assistant chief of service at Grady Memorial Hospital. K. Jeff Carney is an assistant professor of urology in the Department of Urology at Emory University School of Medicine and chief of urology at Grady Memorial Hospital. The authors have indicated no relationships to disclose relating to the content of this article. © 2014 American Academy of Physician Assistants.