How to recognize and treat childhood leukemiaZappolo, Kayla; DeFeo, Danielle; Dang, David; Covino, Jean DHSc, MPA, PA-CJournal of the American Academy of Physician Assistants: July 2013 - Volume 26 - Issue 7 - p 37–41 doi: 10.1097/01.JAA.0000431503.15874.2e Review Article Abstract Author Information ABSTRACT Acute leukemia may be difficult to diagnose in children because of the lack of specific findings. The key is to recognize unexplained symptoms and consider leukemia as a differential. Prompt treatment improves outcomes. Kayla Zappolo, Danielle DeFeo, and David Dang are physician assistant students at Pace University-Lenox Hill Hospital in New York City. Jean Covino is an associate clinical professor at Pace University. The authors have indicated no relationships to disclose relating to the content of this article. © 2013 American Academy of Physician Assistants.