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Total Knee Arthroplasty in Patients With Cerebral Palsy: A Matched Cohort Study to Patients With Osteoarthritis

Houdek, Matthew T. MD; Watts, Chad D. MD; Wyles, Cody C. MD; Trousdale, Robert T. MD; Milbrandt, Todd J. MD; Taunton, Michael J. MD

Journal of the American Academy of Orthopaedic Surgeons: May 2017 - Volume 25 - Issue 5 - p 381–388
doi: 10.5435/JAAOS-D-16-00437
Research Article

Introduction: Currently, few data examine the use of total knee arthroplasty (TKA) in patients with cerebral palsy (CP). This study reviewed the outcomes of TKA in patients with CP compared with a matched cohort undergoing TKA for primary osteoarthritis.

Methods: Over a 28-year period, 15 TKAs in patients with a diagnosis of CP were identified. The cohort was 53% men, with a mean age of 58 years. Patients with CP were matched 1:2 based on age, sex, body mass index, and year of surgery with a group of patients undergoing TKA for osteoarthritis.

Results: No difference was reported in implant survival (P = 0.27) or revision surgery (P = 0.79) between groups. All patients were ambulatory postoperatively, and significant increases were noted in the Knee Society score (P < 0.0001) and functional assessment (P = 0.003).

Discussion: TKA is a safe, durable procedure in patients with CP to improve pain and function.

From the Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.

Correspondence to Dr. Houdek: houdek.matthew@mayo.edu

Dr. Trousdale or an immediate family member has received royalties from DePuy Synthes and Medtronic; serves as a paid consultant to DePuy Synthes; and serves as a board member, owner, officer, or committee member of the American Association of Hip and Knee Surgeons, The Hip Society, and The Knee Society. Dr. Milbrandt or an immediate family member serves as a paid consultant to Orthopediatrics; has stock or stock options held in Viking Scientific; has received nonincome support (such as equipment or services), commercially derived honoraria, or other non-research–related funding (such as paid travel) from Broadwater; and serves as a board member, owner, officer, or committee member of the American Academy of Orthopaedic Surgeons, the Pediatric Orthopaedic Society of North America, and the Scoliosis Research Society. Dr. Taunton or an immediate family member has received royalties from and serves as a paid consultant to DJ Orthopaedics; has received research or institutional support from Stryker; and serves as a board member, owner, officer, or committee member of the American Academy of Orthopaedic Surgeons and the Minnesota Orthopaedic Society. None of the following authors or any immediate family member has received anything of value from or has stock or stock options held in a commercial company or institution related directly or indirectly to the subject of this article: Dr. Houdek, Dr. Watts, and Dr. Wyles.

Received June 06, 2016

Received in revised form September 20, 2016

Accepted November 10, 2016

© 2017 by American Academy of Orthopaedic Surgeons
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