This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in diagnostic imaging. Articles involving MR and CT are featured. Regarding MR, two articles highlight advanced imaging techniques, one evaluating hippocampal sclerosis at 7 T and the other dynamic liver imaging during free-breathing using compressed sensing. Two additional articles investigate issues concerning the kidney, specifically improvements in estimation of renal ADC and IVIM-derived pure-diffusivity as well as non-invasive detection of renal fibrosis with MT-MRI. Regarding CT, advances utilizing dual energy CT are described involving improved removal of calcified carotid plaques (in extracranial carotid artery disease), improved diagnostic accuracy of segmental pulmonary embolism detection with virtual monoenergetic imaging and iodine perfusion maps, and assessment of the spatial distribution of iron in the normal liver.

​​​Investigative Radiology will publish a special issue on 'Contrast Media' in 2018. The focus is on current significant advances in knowledge regarding contrast media. Relevant topics include basic science investigations, clinical trials, innovative clinical applications, and safety. With regard to clinical papers, all organ and disease areas will be considered. Submitted manuscripts should significantly advance our knowledge concerning contrast media in MR, CT, or ultrasound.

Manuscripts are now being accepted for consideration. The deadline for submission is January 31, 2018. All papers will be subject to peer review by experts in the field and must comply with the Journal's Instructions for Authors.

Val M. Runge, MD, Editor-in-Chief, Investigative Radiology

Current Issue Highlights

Virtual Monoenergetic Imaging and Iodine Perfusion Maps Improve Diagnostic Accuracy of Dual-Energy Computed Tomography Pulmonary Angiography With Suboptimal Contrast Attenuation

Leithner, Doris; Wichmann, Julian L.; Vogl, Thomas J.; More

Investigative Radiology. 52(11):659-665, November 2017.

Modified Dual-Energy Algorithm for Calcified Plaque Removal: Evaluation in Carotid Computed Tomography Angiography and Comparison With Digital Subtraction Angiography

Mannil, Manoj; Ramachandran, Jaychandran; Vittoria de Martini, Ilaria; More

Investigative Radiology. 52(11):680-685, November 2017.

Dynamic Liver Magnetic Resonance Imaging in Free-Breathing: Feasibility of a Cartesian T1-Weighted Acquisition Technique With Compressed Sensing and Additional Self-Navigation...

Kaltenbach, Benjamin; Bucher, Andreas M.; Wichmann, Julian L.; More

Investigative Radiology. 52(11):708-714, November 2017.