Investigative Radiology

December 2016: Val M. Runge, MD, a note from the Editor

This issue of the journal, as always, has many outstanding articles, representing cutting edge research and technology in the field of Diagnostic Imaging. The December issue is part 2 of a two-part special issue on contrast media, with part 1 published in November. The first two articles in the current issue present important work with targeted microbubbles, providing further guidance for future developments.Two articles follow, investigating new classes of contrast media (not based on iodine) for x-ray based imaging, and specifically CT. The final four articles deal with improving patient care, using iodinated contrast media, touching upon safety, adverse reactions, and efficacy.

Special Issue on 'Speed in MR'
​Investigative Radiology will publish a special issue on 'Speed in MR' in 2017. The focus is on current significant advances in knowledge. Relevant topics include basic science investigations, clinical studies, and innovative clinical applications. With regard to clinical papers, all organ and disease areas will be considered. Submitted manuscripts should significantly advance our knowledge concerning methods (and applications therein) for increasing the speed with which data is acquired in MR together with innovative acquisition schemes that improve image quality. The focus of any submission does not necessarily need to be reduced scan time, which is simply one part of speed, with additional possible focuses including image quality, sensitivity, temporal and spatial resolution, and a decrease in image artifacts. Review articles, in particular those that are focused to a specific topic within the more general framework of 'Speed', will also be considered.​

Manuscripts are now being accepted for consideration. The deadline for submission is January 31, 2017. All papers will be subject to peer review by experts in the field and must comply with the Journal's Instructions for Authors.

I look very much forward to receiving your submissions.

Best regards,

Val M. Runge, MD, Editor-in-Chief, Investigative Radiology ​

Current Issue Highlights


Val M. Runge, MD

ISSN: 0020-9996

Online ISSN: 1536-0210

Frequency: 12 issues / year

Ranking: Radiology, Nuclear Medicine, and Medical Imaging 9/124

Impact Factor: 4.887

Safety of the Gadolinium-Based Contrast Agents, A Review
​This review discusses first the background in terms of development of these agents and safety discussions therein, and second their relative stability based both on in vitro studies and clinical observations before and including the advent of nephrogenic systemic fibrosis. This sets the stage for the subsequent focus of the review, the current knowledge regarding accumulation of gadolinium in the brain and specifically the dentate nucleus after intravenous administration of the GBCAs and differentiation among agents on this basis.​