Burns are the most devastating form of trauma as they provide a persistent site for bacterial multiplication. Blood cultures from eighty septicemic burn patients were analyzed. Wound infections accounted for 60% of all the burn infections. Gram positive cocci were present in 33% of positive cultures. Resistant to ≥3 antibiotics was seen in 89% of the isolates. Infection in the burn patients continues to be one of the most challenging concerns for the burn team.