The clinical symptoms of both fungal and bacterial dissemination are very similar. In the setting of prolonged neutropenia, abscesses in the liver and other organs are more likely to be of fungal origin. Certain fungi have unique patterns and characteristics that can help with radiological identifi cation. Fungal pathogens have the propensity to exhibit angioinvasion, causing tissue necrosis rather than pus, as seen with bacterial abscesses. Early diagnosis and preemptive antifungal therapy is crucial for improved outcomes.