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Pseudo-Romaña Sign Due to Botfly Infestation

Granada, Michele D. MD*; Samaniego, Susana B. MD; Cantey, Paul T. MD, MPH; Gall, Wayne K. PhD§; Wormser, Gary P. MD*

Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e3182910363
Case Reports

Abstract: We report a patient who presented with unilateral periorbital edema after a short-term travel to an endemic area for Chagas disease and exposure to triatomine (reduviid) bugs. The diagnosis, however, was furuncular myiasis, not Chagas disease. This case emphasizes that there are multiple parasitic agents besides Trypanosoma cruzi that may be associated with clinical findings consistent with Romaña sign.

Author Information

From the *Division of Infectious Diseases, Department of Medicine and †Department of Surgery, New York Medical College, Valhalla, NY; ‡Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA and §New York State Department of Health, Buffalo, NY.

Correspondence to: Michele D. Granada, MD, Chest, Infectious Diseases and Critical Care Associates, P.C. 1601 NW 114th St., Suite 347 Des Moines, IA 50325. E-mail:

The authors have no funding or conflicts of interest to disclose.

The findings and conclusions in this article are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention or the New York State Department of Health.

© 2014 by Lippincott Williams & Wilkins.