Skip Navigation LinksHome > March 2014 - Volume 22 - Issue 2 > Treatment of Disseminated Rhizomucor With a Combination of A...
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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31828941d5
Review Articles

Treatment of Disseminated Rhizomucor With a Combination of Ambisome and Posaconazole

Pak, Jane MD*; Tucci, Veronica T. JD, MD*; Katayama, Mitsuya MD*; Vincent, Albert L. PhD*; Sandin, Ramon L. MD, MS†§; Greene, John N. MD‡∥

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Abstract

Although rare in the general population, mucormycosis can become a rapidly progressive and lethal opportunistic infection in the ketone and carbohydrate-rich milieu of diabetes mellitus and in other conditions. In the past 2 decades, an increasing number of mucormycosis cases have appeared after immunosuppressive treatment for leukemia or bone marrow transplant. We present a case of a patient with acute lymphoblastic leukemia who developed extensively disseminated Rhizomucor infection after chemotherapy. We also discuss the etiology, epidemiology, presentations, diagnoses, and treatment of these increasingly common mucormycosis infections.

Copyright © 2014 by Lippincott Williams & Wilkins

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