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Alopecia Areata in a Human Immunodeficiency Virus–Seropositive Young Man

Kurtz, Maria DO*; Wenner, Kimberly MD; Schofield, Christina MD

Infectious Diseases in Clinical Practice: January 2014 - Volume 22 - Issue 1 - p 57–59
doi: 10.1097/IPC.0b013e318287c368
Case Reports

Alopecia in a human immunodeficiency virus (HIV) population requires a broad differential. We present a case of alopecia in an HIV-infected patient with a recent history of latent syphilis that was clinically consistent with alopecia areata (AA). Ultimately, biopsy demonstrated AA, and the patient responded to intralesional steroid injections. The occurrence of AA, an autoimmune disease with perifollicular inflammation of predominantly CD4+ and CD8+ cells, in HIV infection has been described in a few case reports, and our case highlights the importance of the biopsy. We will explore the association of autoimmunity and HIV and the various theories into the pathogenesis of AA in the HIV population.

From the Departments of *Internal Medicine, †Dermatology, and ‡Infectious Disease, Madigan Army Medical Center, Tacoma, WA.

Correspondence to: Maria Kurtz, DO, Department of Internal Medicine, Madigan Army Medical Center, 9040 Fitzsimmons Blvd, Tacoma, WA 98431. E-mail: maria.kurtz@amedd.army.mil.

The views expressed are those of the author(s) and do not reflect the official policy of the Department of the Army, the Department of Defense, or the US government.

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