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Topical Clindamycin Use for Chest Wall Folliculitis Complicated by Severe Clostridium difficile Infection

Palla, Jyothsna MD*; Imam, Syed N. MD†‡; Yu, Brian MD§∥; Johnson, Stuart MD, FIDSA, DTM&H¶#

Infectious Diseases in Clinical Practice: November 2013 - Volume 21 - Issue 6 - p 410–411
doi: 10.1097/IPC.0b013e318280d93b
Case Report

Abstract: Oral clindamycin use is a recognized risk factor for Clostridium difficile infection (CDI). However, few cases have been reported associating topical clindamycin use with CDI. We report a case of severe CDI related to topical clindamycin phosphate application for folliculitis caused by a highly clindamycin-resistant strain of C difficile.

From the Departments of *Geriatric Medicine, †Geriatrics and Extended Care, Edward Hines Jr. VA Hospital, Hines, IL; ‡Department of Medicine, Loyola University Medical Center, Maywood, IL; §Department of Infectious Diseases, Edward Hines Jr. VA Hospital, Hines, IL; ∥Loyola University Medical Center, Maywood, IL; ¶Infectious Disease Division, Department of Infectious Diseases, Loyola University Medical Center, Maywood, IL; and #Research Service, Edward Hines Jr. VA Hospital, Hines, IL.

Correspondence to: Jyothsna Palla, MD, Department of Geriatric Medicine, Edward Hines Jr. VA Hospital, Hines, IL 6420 Double Eagle Dr, Unit 904, Woodridge, IL 60517. E-mail: joshnaa_p@yahoo.com.

The authors have no funding or conflicts of interest to disclose.

Stuart Johnson, MD is supported by the US Department of Veterans Affairs Research Service.

© 2013 by Lippincott Williams & Wilkins.