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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31826e81b3
Case Reports

Gastric Mucormycosis Managed With Combination Antifungal Therapy and No Surgical Debridement

Katta, Joseph MD*; Gompf, Sandra G. MD, FACP; Narach, Tienchai MD*; Poetter, Daniel MD; Kulkarni, Prasad MD§; Reed, Jennifer MD; Goldsmith, Susan F. MD

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Abstract

Invasive zygomycosis is the second most common opportunistic mold infection after invasive aspergillosis among patients with hematological malignancies and transplant recipients, and cure typically requires extensive debridement. Gastric zygomycosis is infrequently reported yet highly lethal, despite aggressive interventions that include gastrectomy and extended intravenous antifungal therapy. We believe ours to be the second reported case of gastric zygomycosis cured without the morbidity of gastrectomy, using extended lipid-based amphotericin B and posaconazole.

Copyright © 2012 by Lippincott Williams & Wilkins

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