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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e318255d43e
Case Reports

Recurrent Localized Aspergillus Esophagitis in a Patient With Acquired Immunodeficiency Syndrome Who Failed Caspofungin Therapy

Ramanan, Poornima MD*; Sivapalan, Vel MD, FACP*; Schechter, Menachem MD; Culpepper-Morgan, Joan MD

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Abstract

Abstract: Candida esophagitis is a common complication of AIDS, usually presenting with odynophagia. We report the case of a young woman with persistent symptoms despite antifungal therapy who was found to have invasive Aspergillus infection isolated to the esophagus, which promptly resolved with the introduction of lipid complex amphotericin. This case highlights the need to consider fungi other than Candida in the immunosuppressed patient with esophagitis, especially if unresponsive to first-line therapy.

© 2012 Lippincott Williams & Wilkins, Inc.

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