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Disseminated Catscratch Disease, “A Tail of Two Sisters”

Bergamo, Dale F. MD

Infectious Diseases in Clinical Practice: July 2012 - Volume 20 - Issue 4 - p 280–281
doi: 10.1097/IPC.0b013e3182506d76
Case Reports

Abstract: Two siblings presented with fever and gastrointestinal symptoms, including abdominal pain. Imaging studies of the liver and spleen revealed hypoechoic lesions. Liver biopsy demonstrated granulomatous lesions DNA polymerase chain reaction positive for Bartonella henselae. Bartonella immunoglobulin M and immunoglobulin G antibody testing were positive. Both patients responded to antibiotics active against Bartonella henselae.

This report demonstrates an unsual familial presentation of a zoonotic infection, Cat Scratch Disese (CSD). Bergamo discusses the uncommon disseminated/hepatosplenic form of the infection and illustrate the importance of epidemiologic information and family history in order to guide the work-up and arrive at the correct diagnosis. A review of the literature is presented.

From the Division of Infectious Diseases, Department of Pediatrics, University of South Florida, Tampa, FL.

Correspondence to: Dale F. Bergamo, MD, Division of Infectious Diseases, Department of Pediatrics, University of South Florida, 17 Davis Blvd, Suite 200, Tampa, FL 33606. E-mail: dbergamo@health.usf.edu.

The author has no funding or conflicts of interest to disclose.

© 2012 Lippincott Williams & Wilkins, Inc.