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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e318209948b
Case Reports

Successful Use of Daptomycin and Linezolid, Without Surgical Intervention, in the Treatment of Extensive Epidural Abscess and Bacteremia Due to Methicillin-Resistant Staphylococcus aureus (MRSA)

Lane, Jason William MD*; Tang, Jevon MD†; Taggard, Derek MD*; Byun, Raymond MD‡

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Abstract

Spinal epidural abscess infections have traditionally been treated with surgical drainage followed by prolonged administration of antibiotics. We present a case of multifocal methicillin-resistant Staphylococcus aureus infection in a patient with an extensive spinal epidural abscess spanning 11 vertebral bodies, bacteremia, left lower extremity cellulitis, and pneumonia. The infection resolved with combination antimicrobial therapy with daptomycin and linezolid and without drainage of the epidural abscess.

© 2011 Lippincott Williams & Wilkins, Inc.

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