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Successful Use of Daptomycin and Linezolid, Without Surgical Intervention, in the Treatment of Extensive Epidural Abscess and Bacteremia Due to Methicillin-Resistant Staphylococcus aureus (MRSA)

Lane, Jason William MD*; Tang, Jevon MD†; Taggard, Derek MD*; Byun, Raymond MD‡

Infectious Diseases in Clinical Practice: September 2011 - Volume 19 - Issue 5 - pp 362-364
doi: 10.1097/IPC.0b013e318209948b
Case Reports

Spinal epidural abscess infections have traditionally been treated with surgical drainage followed by prolonged administration of antibiotics. We present a case of multifocal methicillin-resistant Staphylococcus aureus infection in a patient with an extensive spinal epidural abscess spanning 11 vertebral bodies, bacteremia, left lower extremity cellulitis, and pneumonia. The infection resolved with combination antimicrobial therapy with daptomycin and linezolid and without drainage of the epidural abscess.

From the *David Grant USAF Medical Center, Travis AFB, Fairfield, CA; †University of California Davis Medical Center; Sacramento, CA and ‡Mather Veterans Affairs Hospital, Sacramento, CA.

Correspondence to: Jason William Lane, MD, 101 Bodin Circle, 60MDG/MDOS/SGOMI, Travis AFB, CA 94535. E-mail: jason.lane@us.af.mil.

The authors have no funding or conflicts of interest to disclose.

The views expressed in this material are those of the authors and do not reflect the official policy or position of the US Government, the Department of Defense, the Department of the Air Force, or the Veterans Administration.

© 2011 Lippincott Williams & Wilkins, Inc.