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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e318209973c
Case Reports

Abnormal Positron Emission Tomographic Scan Due to Undiagnosed Adrenal Histoplasmosis

Gelfand, Michael S. MD*; Cleveland, Kerry O. MD*; Baskin, Reed C. MD†

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Abstract

Infection with Histoplasma capsulatum may result in clinical signs and symptoms consistent with malignancy or infection. Microbiologic and immunologic diagnostic tests for histoplasmosis may yield false-negative results and lead to additional testing for the malignancies it may mimic. We report a patient with negative initial study results for infection who was found on evaluation to have bilateral adrenomegaly and adrenal uptake on 18F-fluorodeoxyglucose positron emission tomography suggestive of a neoplastic process. On further testing, the patient was found to have adrenal histoplasmosis.

© 2011 Lippincott Williams & Wilkins, Inc.

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