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Primary Autoimmune Neutropenia Uncovered by Methicillin-Resistant Staphylococcus aureus Osteomyelitis

Kunkel, Melissa A. MD*†; Moertel, Christopher L. MD‡; John, Chandy C. MD, MS*†

Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e3181db80d8
Case Reports

Primary autoimmune neutropenia (AIN) is an uncommon and typically benign form of neutropenia. We describe a case of primary AIN uncovered by methicillin-resistant Staphylococcus aureus osteomyelitis. This is a more severe infection than would be expected with primary AIN, but as is typical of primary AIN, the course was uncomplicated. Primary AIN should be investigated in patients with infection and persistent neutropenia.

Author Information

From the *Division of Pediatric Infectious Diseases, †Center for Global Pediatrics, and ‡Division of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN.

Reprints: Chandy C. John, MD, MS, Center for Global Pediatrics, Department of Pediatrics, University of Minnesota Medical School, 717 Delaware St SE, Room 363, Minneapolis, MN 55455. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.