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Failure of Caspofungin for Treatment of Candida glabrata Candiduria: Case Report and Review of the Literature

Malani, Anurag N. MD

Infectious Diseases in Clinical Practice: July 2010 - Volume 18 - Issue 4 - pp 271-272
doi: 10.1097/IPC.0b013e3181d04a1d
Case Reports

The echinocandins have not been studied for the treatment of Candida urinary tract infections. Current evidence in a small number of patients notes both success and failure.

I report nonresponse to treatment with caspofungin associated with the rapid development of resistance in a 64-year-old woman with a complicated C. glabrata urinary tract infection. Until further clinical data are available, the echinocandins should be used with caution for the treatment of complicated C. glabrata urinary tract infections.

From the Section of Infectious Diseases and Department of Internal Medicine, St Joseph Mercy Health System, Ypsilanti, MI.

Reprints: Anurag N. Malani, MD, St Joseph Mercy Health System, Suite 3106, 5333 McAuley Dr, Ypsilanti, MI 48197. E-mail: malanian@umich.edu.

The author has no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.