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Respiratory Failure and Antineutrophil Cytoplasmic Antibody-Positive Vasculitis Associated With Rothia mucilaginosa Endovascular Infection: A Rare Case and Review of the Literature

Jobanputra, Taral MD*; Carson, Michael P. MD*†; Frank, Elliot MD*; Daniels, Steven MD*; Costanzo, Eric DO*; Shah, Purviben MD*; Erler, Brian MD‡

Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e3181d5e1bd
Review Articles

Infections with Rothia mucilaginosa are unusual in immunocompetent hosts and have not been associated with vasculitis. We present the first report of an endovascular pacemaker wire infection with R. mucilaginosa causing respiratory failure due to atypical antineutrophil cytoplasmic antibody-associated vasculitis, a brief overview of the clinical spectrum of infection with this unusual pathogen, and review the implications of a positive antineutrophil cytoplasmic antibody in the setting of endovascular infection.

Author Information

From the Departments of *Medicine, Jersey Shore University Medical Center; and †UMDNJ-Robert Wood Johnson Medical School; and ‡Department of Pathology, Jersey Shore University Medical Center, Neptune, NJ.

Reprints: Michael P. Carson, MD, Department of Medicine, Jersey Shore University Medical Center, Ackerman 3, 1945 Route 33, Neptune, NJ 07753. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.