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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e3181d5e1bd
Review Articles

Respiratory Failure and Antineutrophil Cytoplasmic Antibody-Positive Vasculitis Associated With Rothia mucilaginosa Endovascular Infection: A Rare Case and Review of the Literature

Jobanputra, Taral MD*; Carson, Michael P. MD*†; Frank, Elliot MD*; Daniels, Steven MD*; Costanzo, Eric DO*; Shah, Purviben MD*; Erler, Brian MD‡

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Abstract

Infections with Rothia mucilaginosa are unusual in immunocompetent hosts and have not been associated with vasculitis. We present the first report of an endovascular pacemaker wire infection with R. mucilaginosa causing respiratory failure due to atypical antineutrophil cytoplasmic antibody-associated vasculitis, a brief overview of the clinical spectrum of infection with this unusual pathogen, and review the implications of a positive antineutrophil cytoplasmic antibody in the setting of endovascular infection.

© 2010 Lippincott Williams & Wilkins, Inc.