Rhinocerebral mucormycosis (RCM) is an increasingly common infection in immunocompromised subjects. We report a case of RCM in an immunosuppressed gentleman known to suffer from sigmoid colon adenocarcinoma stage D and presenting with diabetic ketoacidosis, complete ptosis, and orbital cellulitis. During his hospital stay, the patient developed cranial diabetes insipidus. In spite of extensive surgical debridement and high-dose liposomal amphotericin, the disease had a fatal outcome. This case emphasizes the need for increased awareness of mucormycosis as a potentially lethal fungal infection requiring a high index of suspicion in subjects at risk. The case also illustrates a rare complication of RCM, namely diabetes insipidus.
From the *Diabetes and Endocrine Centre, †Department of Infectious Diseases and ‡Ears, Nose and Throat Department, Mater Dei Hospital, Tal-Qroqq, Malta.
Reprints: Caroline Jane Magri, MD, MRCP, "Jesmel," Imdina Rd, Zebbug ZBG 05, Malta. E-mail: email@example.com; firstname.lastname@example.org.
The authors have no funding or conflicts of interest to disclose.