A patient with human immunodeficiency virus having lymphadenoma, hepatosplenomegaly, fever, and weight loss was referred to the hospital. Because of a massive rise of procalcitonin, an extensive antibiotic therapy was initiated which, however, did not result in any clinical improvement. Tissue diagnosis revealed a multicentric Castleman disease. After consecutive chemotherapy, procalcitonin levels decreased by less than 3 log suggesting a causative role of multicentric Castleman disease.
From the *Departments of Internal Medicine I (Gastroenterology, Hepatology, Infectious Diseases) and †Internal Medicine II (Hematology, Oncology, Immunology), University Hospital Tübingen, Tübingen, Germany.
Reprints: Alfred Lennart Bissinger, MD, Department of Internal Medicine I, University Hospital Tübingen, Otfried-Müller-Strasse 10, D-72076 Tübingen, Germany. E-mail: firstname.lastname@example.org.
The authors have no funding or conflicts of interest to disclose.