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Fulminant Hepatitis During Legionella Pneumophila Infection

Mofredj, Ali MD*; Bahloul, Hichem MD*; Mrabet, Affef MD*; Gineyt, Guy MD*; Rousselier, Patricia MD†

Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31818ec244
Case Reports

Legionella pneumophila is a common cause of unusually severe pneumonia with multisystem dysfunction. Extrapulmonary manifestations such as myalgias, gastrointestinal, and neurological symptoms may sometimes be predominant with an impressive severity. Abnormalities in laboratory values are likewise nonspecific and can include features of hepatic and renal dysfunction. However, acute liver failure has never been described as the most prominent syndrome. We report a case of fulminant hepatitis probably due to Legionella infection.

Author Information

From the *Service de Réanimation and †Laboratoire de Microbiologie, Centre Hospitalier Général, Salon de Provence, France.

Reprints: Ali Mofredj, MD, Service de Réanimation, Centre Hospitalier Général, 13300 Salon de Provence, France. E-mail:

© 2009 Lippincott Williams & Wilkins, Inc.