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Progression From Free Floating Left Ventricular Vegetation to Immobile Mitral Valve in a Child With Zygomyces Endocarditis

Janssen, Sarah F.*; Rammeloo, Lukas A. MD*; Schoof, Paul H. MD, PhD†; Kaspers, Gertjan J. L. MD, PhD‡; Hruda, Jaroslav MD, PhD*

Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31818cd638
Case Reports

Establishing the diagnosis of fungal endocarditis caused by zygomyces during life occurs rarely. We report on a child in whom zygomyces mitral valve endocarditis has developed. Floating thrombus attached to the mitral papillary muscles protruded in systole from the left ventricle into the aorta. Despite adequate medical and surgical treatment, this lesion recurred postoperatively with development of severe mitral obstruction and subsequent death.

Author Information

From the *Department of Pediatric Cardiology, VU University Medical Center, Amsterdam; †Cardiothoracic Surgery, Leiden University Medical Center, Leiden; and ‡Pediatric Oncology and Hematology, VU University Medical Center, Amsterdam, The Netherlands.

Reprints: Jaroslav Hruda, MD, PhD, Department of Pediatric Cardiology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. E-mail:

© 2009 Lippincott Williams & Wilkins, Inc.