Skip Navigation LinksHome > July 2009 - Volume 17 - Issue 4 > Plasmablastic Lymphoma Masquerading as Perianal Abscess in a...
Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31818d1aee
Case Reports

Plasmablastic Lymphoma Masquerading as Perianal Abscess in a Homosexual Man

Rapose, Alwyn MD*; Naniwadekar, Ashutosh MD†

Collapse Box

Abstract

Perianal abscess is a common condition treated surgically with early incision and drainage. It is commonly associated with bowel flora and less often with skin flora. However, in individuals with history of receptive anal intercourse, sexually transmitted infections like gonorrhea should also be considered. We report a case of a 46-year-old HIV-positive homosexual man who presented with features of a perianal abscess. However, no organisms were obtained on cultures. Instead, tissue biopsy revealed plasmablastic lymphoma-a very rare and highly aggressive variant of non-Hodgkin lymphoma. The unique features in our patient were the very unusual presentation in the form of acute perianal swelling mimicking an abscess and the absence of advanced HIV disease (his CD4 count was 973 cells/μL).

In HIV-positive individuals presenting with features of perianal abscesses, the differential diagnosis should be expanded to include not only sexually transmitted infections but also malignancies like lymphoma.

© 2009 Lippincott Williams & Wilkins, Inc.