Skip Navigation LinksHome > May 2009 - Volume 17 - Issue 3 > Pancreatitis, Diarrhea, and Glycopeptide Dependence
Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31818718fd
Case Reports

Pancreatitis, Diarrhea, and Glycopeptide Dependence

Soleimanian, Sorrush MD*; Wareham, David W. PhD*†

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Abstract

We describe an interesting case of bacteremia due to a strain of Enterococcus faecium dependent on glycopeptides for growth. The infection occurred after vancomycin treatment of Clostridium difficile antibiotic-associated diarrhea. The strain required a minimum of 0.25 mg/L of vancomycin or 0.094 mg/L of teicoplanin and reverted to nondependence at a frequency of 2.6 × 10−3. Laboratories should be vigilant for the emergence of similar strains during prolonged glycopeptide therapy, which may be difficult to detect with current laboratory practices.

© 2009 by Lippincott Williams & Wilkins.