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Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e31818add36
Review Articles

Sporotrichosis in Human Immunodeficiency Virus Infected Peruvian Patients: Two Case Reports and Literature Review

Bustamante, Beatriz MD*†; Lama, Javier R. MD, MPH‡; Mosquera, Carlos MD‡; Soto, Leslie MD†§

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Abstract

Two cases of sporotrichosis in persons with human immunodeficiency virus (HIV) infection are reported. Both patients traveled and/or lived in rural areas recognized either as endemic or from where some other non HIV-related cases were reported. In the first case, the patient had a systemic disease with cutaneous, subcutaneous, bone marrow and multiple joint involvement. In the second case, disseminated tuberculosis was concomitantly diagnosed by the time of sporotrichosis diagnosis. Both patients had a good clinical response to intravenous amphotericin B used as primary therapy. Discussions about the clinical aspects and probable pathogenesis and a review of current literature are conducted.

© 2009 Lippincott Williams & Wilkins, Inc.