Skip Navigation LinksHome > September 2008 - Volume 16 - Issue 5 > Mycobacterium africanum Presenting as a Brain Mass
Infectious Diseases in Clinical Practice:
doi: 10.1097/IPC.0b013e3181637a0f
Case Reports

Mycobacterium africanum Presenting as a Brain Mass

Bhanot, Nitin MD; Badem, Olga MD; Mathew, Liby MD; Haran, Mehandi MD

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Abstract

A 27-year-old woman, who had emigrated from Sierra Leone 5 years prior, presented with worsening headaches of 3-month duration. Magnetic resonance imaging of the brain revealed a lobulated mass lesion with central necrosis in the right parietal and occipital lobes. Biopsy was performed, and histopathology revealed multiple granulomas. Although acid-fast stain of the tissue was negative, gene probe showed Mycobacterium tuberculosis complex, and culture revealed Mycobacterium africanum. This species is rare in the United States, and to the best of our knowledge, this is the first reported case of M. africanum causing a brain mass.

© 2008 Lippincott Williams & Wilkins, Inc.

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