Skip Navigation LinksHome > November 2014 - Volume 24 - Issue 9 > Gynecologic Cancer InterGroup (GCIG) Consensus Review for Sq...
International Journal of Gynecological Cancer:
doi: 10.1097/IGC.0000000000000209
Review Articles

Gynecologic Cancer InterGroup (GCIG) Consensus Review for Squamous Cell Carcinoma of the Ovary

Glasspool, Rosalind M. MBBS, PhD, FRCP*; Martín, Antonio González MD; Millan, David BSc, MB ChB, FRCPath; Lorusso, Domenica MD§; Åvall-Lundqvist, Elisabeth MD, PhD; Hurteau, Jean A. MD; Davis, Alison MBBS, MSc, FRACP#; Hilpert, Felix MD, PhD**; Kim, Jae-Weon MD, PhD††; Alexandre, Jérôme MD, PhD‡‡; Ledermann, Jonathan A. MD, FRCP§§

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Abstract

Squamous cell carcinoma of the ovary is a rare complication of mature cystic teratoma. The epidemiology, pathology, diagnosis, and management of this rare tumor are reviewed. Clinical characteristics, preoperative imaging, and tumor markers may help to predict malignancy preoperatively. Complete cytoreduction should be the aim of surgery. The prognosis for stage 1A disease is good, but for women with advanced or recurrent disease, it is very poor and has not improved in recent years. At present, there are insufficient data to provide clear guidance on the optimal management strategy for advanced disease, and there is a need to gain an understanding of the biology and to develop novel effective therapies. This will require coordinated international collaboration.

Copyright © 2014 by IGCS and ESGO

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