Skip Navigation LinksHome > July 2014 - Volume 24 - Issue 6 > Preoperative Ultrasound-Guided Needle Biopsy of 63 Uterine T...
International Journal of Gynecological Cancer:
doi: 10.1097/IGC.0000000000000189
Uterine Cancer

Preoperative Ultrasound-Guided Needle Biopsy of 63 Uterine Tumors Having High Signal Intensity Upon T2-Weighted Magnetic Resonance Imaging

Tamura, Ryo MD*; Kashima, Katsunori MD, PhD*; Asatani, Mina MD, PhD; Nishino, Koji MD, PhD*; Nishikawa, Nobumichi MD, PhD*; Sekine, Masayuki MD, PhD*; Serikawa, Takehiro MD, PhD*; Enomoto, Takayuki MD, PhD*

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Abstract

Objective

The differential diagnosis between uterine sarcoma and benign leiomyoma is difficult when made only by magnetic resonance imaging (MRI); it usually requires an additional preoperative diagnostic procedure. We report our results using ultrasound-guided needle biopsy for these types of uterine tumors.

Methods

Ultrasound-guided needle biopsy was performed on 63 patients with uterine smooth muscle tumors suspected of malignancy by MRI. We compared the results of presurgical biopsy against the postsurgical pathology of the tumor.

Results

Among 63 patients with a high signal intensity of the uterine tumor on T2-weighted MRI (1 case was undetermined), 12 cases (19.3%) were diagnosed by the needle biopsy as malignant, and 51 cases (80.6%) were benign. Among the 12 diagnosed as malignant tumors, 11 had surgery performed, and one was treated with chemotherapy. Among the 51 patients diagnosed with a benign tumor, 27 had surgery performed, and 24 were put on a wait-and-see clinical follow-up schedule. One of the 27 surgical patients with a benign tumor had a postsurgical diagnosis of a low-grade endometrial stromal sarcoma. In the 38 cases where surgery was performed, we found the sensitivity, specificity, and the positive and negative predictive values of the needle biopsy were 91.7%, 100%, 100%, and 96.2%, respectively.

Conclusions

Ultrasound-guided needle biopsy may be a reliable preoperative diagnostic procedure for uterine tumors with suspected malignancy.

Copyright © 2014 by IGCS and ESGO

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