Skip Navigation LinksHome > February 2013 - Volume 23 - Issue 2 > Analysis of a Continuous Series of 34 Young Patients With Ea...
International Journal of Gynecological Cancer:
doi: 10.1097/IGC.0b013e31827ef759
Cervical Cancer

Analysis of a Continuous Series of 34 Young Patients With Early-Stage Cervical Cancer Selected for a Vaginal Radical Trachelectomy: Should “Staging” Conization Be Systematically Performed Before This Procedure?

Uzan, Catherine MD, PhD*†; Gouy, Sebastien MD*; Desroque, Delphine MD*; Pomel, Christophe MD, PhD; Duvillard, Pierre MD§; Balleyguier, Corrine MD; Haie-Meder, Christine MD; Morice, Philippe MD, PhD*#

Collapse Box


Objective: Vaginal radical trachelectomy (VRT) is the most widely evaluated form of conservative management of young patients with early-stage (IB1) cervical cancer. Patients with nodal involvement or a tumor size greater than 2 cm are not eligible for such treatment. The aim of this study is to report the impact of a “staging” conization before VRT.

Methods: This is a retrospective study of 34 patients potentially selected for VRT for a clinical and radiologic cervical tumor less than 2 cm. Among them, 28 underwent finally a VRT (20 of them having a previous conization before this procedure) and 6 patients with macroscopic cervical cancer, confirmed by punch biopsies, “eligible” for VRT (<2 cm) had undergone “staging” conization (without further VRT) to confirm the tumor size and lymphovascular space involvement (LVSI) status.

Results: Six patients having “staging” conization before VRT had finally been deemed contraindications to VRT due to the presence of a histologically confirmed tumor greater than 2 cm and/or associated with multiple foci of LVSI. Among 28 patients who underwent VRT, 1 received adjuvant chemoradiation (this patient recurred and died of disease). Two patients treated with RVT (without postoperative treatment) recurred. Ten pregnancies (9 spontaneous and 1 induced) were observed in 9 patients. Among 4 patients with macroscopic “visible” tumor who do not underwent a “staging” conization before VRT, 2 recurred. Among 11 patients who underwent VRT and having LVSI, 3 recurred.

Conclusions: These results suggest that if a conization is not performed initially, it should then be included among the staging procedures to select patients for VRT.

Copyright © 2013 by IGCS and ESGO


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us


For additional oncology content, visit LWW Oncology Journals on Facebook.