BACKGROUND: Recently reported trends in hospitalization of children with Inflammatory Bowel Disease (IBD) show increasing hospitalization rates for unclear reasons. Short stays in the hospital may contribute to this increase. Aims: To characterize the trend and investigate potential contributors to short stay hospitalizations and impact upon overall hospitalizations for children and young adults with IBD.METHODS: We analyzed hospital stays with a discharge diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) within the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample database. Short stay hospitalizations were defined as <2 days. Rates of short stay hospitalizations per 100 IBD hospitalizations were calculated with 95% confidence intervals (CI) being reported.RESULTS: Percent of IBD-hospitalizations that were short stay rose slowly from 7.9% (95% CI: 7.2-8.3) in 1988 to 12.0% (95% CI: 11.9-12.1) in 2000 and subsequently remained stable (Fig. 1). Coding for infliximab infusions were present in only 0.08% of IBD hospitalizations of any length of stay. There was little change in IBD short stay hospitalizations with surgery from 2.0% (95% CI: 1.2-2.4) to 2.6% (95% CI: 1.5-3.3) of surgery hospitalizations. IBD short stay hospitalizations with endoscopy rose from 4.0% (95% CI: 2.7-4.9) of IBD hospitalizations in 1991 transiently to 9.1% (95% CI: 7.2-10.4) in 1999-2000 before returning to previous levels (Fig. 2).CONCLUSIONS: Short stay hospitalization rates increased from 1988 to 2000 and have since remained constant. Short stay hospitalizations, whether for same-day Infliximab infusions, same-day surgeries or same-day endoscopy, did not substantially contribute to the overall rise in hospitalization rates for children and young adults with IBD in the United States.(C) Crohn's & Colitis Foundation of America, Inc.