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Three-Dimensional Geometry of the Heineke–Mikulicz Strictureplasty

Pocivavsek, Luka MD, PhD*; Efrati, Efi PhD†,‡; Lee, Ke Y.C. PhD†,§; Hurst, Roger D. MD

doi: 10.1097/MIB.0b013e3182802be3
Original Basic Science Articles

Background: The objective of this study was to assess the regional geometry of the Heineke–Mikulicz (HM) strictureplasty. The HM intestinal strictureplasty is commonly performed for the treatment of stricturing Crohn's disease of the small intestine. This procedure shifts relatively normal proximal and distal tissue to the point of narrowing and thus increases the luminal diameter. The overall effect on the regional geometry of the HM strictureplasty, however, has not been previously described in detail.

Methods: HM strictureplasties were created in latex tubing and cast with an epoxy resin. The resultant casts of the lumens were then imaged using computed tomography. Using 3-dimensional vascular reconstruction software, the cross-sectional areas were determined and the surface geometry was examined.

Results: The HM strictureplasty, while increasing the lumen at the point of the stricture, also results in a counterproductive luminal narrowing proximal and distal to the strictureplasty. Within the model used, cross-sectional area was diminished 25% to 50% below baseline. This effect is enhanced when 2 strictureplasties are placed in close proximity to each other.

Conclusions: The HM strictureplasty results in alterations in the regional geometry that may result in a compromise of the lumen proximal and distal to the location of the strictureplasty. When 2 HM strictureplasties are created in close proximity to each other, care should be undertaken to assure that the lumen of the intervening segment is adequate.

Supplemental Digital Content is Available in the Text.Article first published online 27 February 2013

*Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania;

James Franck Institute, University of Chicago, Chicago, Illinois; and

Departments of Physics,

§Chemistry, and

Surgery, University of Chicago, Chicago, Illinois.

Reprints: Roger D. Hurst, MD, University of Chicago, Pritzker School of Medicine, 5841 South Maryland Avenue, MC-5093, Chicago, IL 60637 (e-mail:

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (

Supported by Simmons Foundation (to E.E.) and the University of Chicago MRSEC program of the NSF (DMR-0820054 to L.P, E.E. and K.Y.C).

The authors have no conflicts of interest to disclose.

Received June 26, 2012

Accepted July 11, 2012

© Crohn's & Colitis Foundation of America, Inc.
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