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Strategies for Detecting Colon Cancer and Dysplasia in Patients with Inflammatory Bowel Disease

Collins, Paul D. MB, BCh

doi: 10.1097/MIB.0b013e3182802c6a
Cochrane Review

Abstract: The risk of colorectal cancer in patients with long-standing ulcerative colitis or colonic Crohn's disease is increased. Patients with long-standing ulcerative colitis are offered enrollment into programs of endoscopic surveillance. Although direct evidence for a protective effect of surveillance against death from colorectal cancer is limited, colorectal cancer is detected at an earlier stage and the corresponding prognosis is better. Targeting biopsies using pancolonic chromoendoscopy is superior to taking multiple random biopsies for the detection of dysplasia at colonoscopy.

Article first published online 26 February 2013

Department of Gastroenterology, Royal Liverpool University Hospital, Liverpool, United Kingdom.

Reprints: Paul D. Collins, MB, BCh, MRCP, Department of Gastroenterology, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, United Kingdom (e-mail: paul.collins@rlbuht.nhs.uk).

The author reports no financial or conflicts of interest to disclose.

Received July 10, 2012

Accepted July 25, 2012

© Crohn's & Colitis Foundation of America, Inc.
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