Background: Paediatric onset inflammatory bowel disease (IBD) may cause alterations in energy requirements and invalidate the use of standard prediction equations. Our aim was to evaluate four commonly used prediction equations for resting energy expenditure (REE) in children with IBD.
Methods: Sixty‐three children had repeated measurements of REE as part of a longitudinal research study yielding a total of 243 measurements. These were compared with predicted REE from Schofield, Oxford, FAO/WHO/UNU, and Harris‐Benedict equations using the Bland‐Altman method.
Results: Mean (±SD) age of the patients was 14.2 (2.4) years. Mean measured REE was 1566 (336) kcal per day compared with 1491 (236), 1441 (255), 1481 (232), and 1435 (212) kcal per day calculated from Schofield, Oxford, FAO/WHO/UNU, and Harris‐Benedict, respectively. While the Schofield equation demonstrated the least difference between measured and predicted REE, it, along with the other equations tested, did not perform uniformly across all subjects, indicating greater errors at either end of the spectrum of energy expenditure. Smaller differences were found for all prediction equations for Crohn's disease compared with ulcerative colitis.
Conclusions: Of the commonly used equations, the equation of Schofield should be used in pediatric patients with IBD when measured values are not able to be obtained. (Inflamm Bowel Dis 2010;)
1 The University of Queensland, Children's Nutrition Research Centre, Royal Children's Hospital, Herston, QLD 4029, Australia
2 Queensland Paediatric Gastroenterology, Hepatology and Nutrition Service, Royal Children's Hospital, Herston, Qld 4029, Australia
3 The University of Queensland, School of Medicine, Herston, Qld 4029, Australia
* Children's Nutrition Research Centre, Discipline of Paediatrics and Child Health, University of Queensland, Level 3 Foundation Building, Royal Children's Hospital, Herston, QLD 4029, Australia
Received 29 July 2010; Accepted 7 September 2010
Published online 4 November 2010 in Wiley Online Library (wileyonlinelibrary.com).
Partially funded by Crohn's and Colitis Australia.