Background: Attrition in longitudinal research negatively affects statistical power, disrupts statistical stability, and can produce unwanted bias.
Objective: To investigate factors associated with shorter length of study participation and lower rates of study completion (ie, attrition) in a large, multisite, longitudinal, randomized, clinical trial examining the efficacy of a Web-based family problem-solving treatment following traumatic brain injury (TBI) in adolescence.
Setting: Five major trauma centers in the central and western regions of the United States.
Participants: Children (N = 132) aged 12 to 17 years hospitalized for complicated mild to severe TBI within the previous 6 months.
Results: Completers had a higher primary caregiver education and higher family income than noncompleters, whereas ethnicity, latency to baseline assessment, and intervention group were not significantly associated with study completion.
Conclusion: This is the first study that has specifically examined factors of attrition in a pediatric TBI population. The results suggest that research on pediatric TBI populations may be biased toward higher-income families and highlights the importance of designing studies with increased awareness of the impact of participant demographic factors.
Children's Hospital Colorado, Aurora (Mr Blaha and Ms Arnett); Children's Hospital Colorado & University of Colorado Denver School of Medicine, Aurora (Dr Kirkwood); Rainbow Babies and Children's Hospital & Case Western Reserve University, Cleveland, Ohio (Dr Taylor); MetroHealth Medical Center & Case Western Reserve University, Cleveland, Ohio (Dr Stancin); Mayo Clinic, Rochester, Minnesota (Dr Brown); and Cincinnati Children's Hospital Medical Center & University of Cincinnati College of Medicine, Cincinnati, Ohio (Dr Wade).
Corresponding Author: Robert Z. Blaha, MA, Department of Rehabilitation Medicine, Children's Hospital Colorado, 13123 E. 16th Ave, B285, Aurora, CO 80045 (email@example.com).
This work was supported in part by (1) NIH grant R01-MH073764 from the National Institute of Mental Health, (2) a grant from the Colorado Traumatic Brain Injury Trust Fund Research Program, Colorado Department of Human Services, Division of Vocational Rehabilitation, Traumatic Brain Injury Program, and (3) a grant from the Department of Education, NIDRR grant number H133B090010-01 (the contents do not necessarily represent the policy of the Department of Education, and endorsement by the Federal Government cannot be assumed).
The authors declare no conflicts of interest.