BACKGROUND: Transgender individuals, individuals whose gender identity does not align with their sex assigned at birth, undergoing gender-affirming hormonal or surgical therapies may experience loss of fertility. Assisted reproductive technologies have expanded family-building options for transgender men who were assigned female at birth.
CASES: Three transgender men underwent oocyte cryopreservation before gender-affirming hormonal therapy. One patient underwent fertility preservation as an adolescent. Two adult patients had children using their cryopreserved oocytes, with the pregnancies carried by their sexually intimate partners.
CONCLUSION: Transgender men with cryopreserved gametes can build families in a way that affirms their gender identity. Obstetrician–gynecologists should be familiar with the fertility needs of transgender patients so appropriate discussions and referrals can be made.
Fertility preservation using assisted reproductive technology expands family-building options for transgender men undergoing gender-affirming therapies.
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, New York University School of Medicine, New York, New York.
Corresponding author: Susan Maxwell, MD, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, New York University School of Medicine, 660 First Avenue, 5th Floor, New York, NY 10016; email: Susan.email@example.com.
Financial Disclosure The authors did not report any potential conflicts of interest.
The authors thank the patients of NYUFC for permitting us to share their fertility preservation stories and Tiffany Cook for her expertise and review of our manuscript.
Each author has indicated that he or she has met the journal's requirements for authorship.