BACKGROUND: Patient–prosthesis mismatch is a known and severe complication after aortic valve repair in the general population. There is a paucity of literature regarding this condition in pregnancy.
CASE: We present the clinical course of a pregnant woman with severe patient–prosthesis mismatch after aortic valve replacement. After extensive workup, the patient underwent aortic valve replacement, enlargement of the aortic root, and placement of a larger prosthetic valve at 21 weeks of gestation. Her postoperative course was complicated by fetal death.
CONCLUSION: Cardiopulmonary bypass and aortic valve replacement present a multitude of risks to maternal and fetal health. The obstetrician managing pregnant women with prosthetic heart valves should be aware of the complications that may arise, including patient–prosthesis mismatch.
Patient&#x2013;prosthesis mismatch is a severe complication after prosthetic valve replacement surgery that may pose significant risk to maternal health during pregnancy.
Department of Obstetrics & Gynecology, University of California Irvine Medical Center, Orange, and Miller Children's Hospital-Long Beach Memorial Medical Center, Long Beach, California.
Corresponding author: Robert C. Johnston, MD, Resident Physician, Department of Obstetrics & Gynecology, UC Irvine Medical Center, 101 The City Drive, Building 56, Suite 800, ZOT 3200 Orange, CA 92868; e-mail: firstname.lastname@example.org.
Financial Disclosure The authors did not report any potential conflicts of interest.