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Spontaneous Liver Rupture Associated With Hydatidiform Mole Pregnancy

Vanatta, Jason M. MD; Monge, Humberto PA-C; Bonham, Clark A. MD; Concepcion, Waldo MD

Obstetrics & Gynecology:
doi: 10.1097/AOG.0b013e3181c692a5
Case Reports

BACKGROUND: Spontaneous liver rupture is a rare occurrence during pregnancy.

CASE: A young woman presented early in her pregnancy with severe abdominal pain, tachycardia, and hypotension. She was taken emergently to the operating room with a presumed diagnosis of ruptured ectopic pregnancy. Exploration revealed that her hemoperitoneum resulted from large fractures within her liver. During her resuscitation and treatment, a transvaginal ultrasound scan revealed a hydatidiform molar pregnancy. On resolution of postoperative complications and complete recovery, the patient was discharged home.

CONCLUSION: This case illustrates that, although very unusual, hydatidiform molar pregnancies should be considered as a precipitating factor for spontaneous liver rupture.

In Brief

Hydatidiform molar pregnancies should be considered as a precipitating factor for spontaneous liver rupture.

Author Information

From the Methodist Transplant Institute/University of Tennessee, Division of Transplantation, Memphis, Tennessee; and Stanford University, Division of Transplantation, Palo Alto, California.

Corresponding author: Jason M. Vanatta, MD, 1265 Union Avenue, 10th Floor, Memphis, TN 38104; e-mail:

Financial Disclosure The authors did not report any potential conflicts of interest.

© 2010 The American College of Obstetricians and Gynecologists