Institutional members access full text with Ovid®

Share this article on:

Diagnostic Dilemmas in a Pregnant Woman With Influenza A (H1N1) Infection

Greer, Laura G. MD; Abbassi-Ghanavati, Mina MD; Sheffield, Jeanne S. MD; Casey, Brian M. MD

doi: 10.1097/AOG.0b013e3181cbc8d0
Case Reports

BACKGROUND: Pregnant women are at increased risk for complications from seasonal influenza. Early data suggest that influenza A (H1N1) may present an even greater risk.

CASE: We present the case of a pregnant woman with severe pulmonary complications from 2009 H1N1 whose care was further complicated by delay in diagnosis and unusual laboratory abnormalities.

CONCLUSION: H1N1 may pose several diagnostic challenges for obstetricians, including increased rates of serious pulmonary complications, decreased sensitivity of rapid tests with delay in initiation of antiviral therapy, and abnormal laboratory findings usually associated with other complications of pregnancy. We document these problems, urge initiation of antiviral therapy based on clinical suspicion, and recognize the potential laboratory abnormalities that may be associated with severe influenza illness.

Influenza A (H1N1) infection in pregnancy is associated with increased rates of influenza-related complications, decreased sensitivity of laboratory testing, and sometimes unexpected laboratory abnormalities.

From the Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, Dallas, Texas.

Corresponding author: Laura Greer, MD, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9032; e-mail: laura.greer@utsouthwestern.edu.

Financial Disclosure The authors did not report any potential conflicts of interest.

© 2010 The American College of Obstetricians and Gynecologists