Skip Navigation LinksHome > February 2009 - Volume 113 - Issue 2, Part 1 > Perinatal Outcome of Monoamniotic Twin Pregnancies
Obstetrics & Gynecology:
doi: 10.1097/AOG.0b013e318195bd57
Original Research

Perinatal Outcome of Monoamniotic Twin Pregnancies

Hack, Karien E. MD, PhD1; Derks, Jan B. MD, PhD1; Schaap, Arty H. MD, PhD3; Lopriore, Enrico MD, PhD4; Elias, Sjoerd G. MD, PhD6; Arabin, Birgit MD, PhD7; Eggink, Alex J. MD, PhD8; Sollie, Krystyna M. MD, PhD9; Mol, Ben Willem J. MD, PhD10; Duvekot, Hans J. MD, PhD11; Willekes, Christine MD, PhD12; Go, Attie T. MD, PhD13; Koopman-Esseboom, Corine MD, PhD2; Vandenbussche, Frank P. MD, PhD5; Visser, Gerard H. MD, PhD1

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OBJECTIVE: To study perinatal mortality and neonatal morbidity in a large cohort of monoamniotic twin pregnancies with special emphasis to the gestational age-specific mortality.

METHODS: The study included monoamniotic twin pregnancies delivered in 10 perinatal centers in the Netherlands between January 2000 and December 2007.

RESULTS: A total of 98 monoamniotic pregnancies were included. The perinatal mortality rate (20 weeks of gestation through 28 days of life) was 19%; after exclusion of fetuses with lethal anomalies, the rate was 17%. After 32 weeks of gestation, only two pregnancies were complicated by perinatal mortality (4%). The incidence of twin–twin transfusion syndrome was 6%. The incidence of congenital heart anomalies and cerebral injury was 4% and 5%, respectively.

CONCLUSION: The current incidence of perinatal mortality in monoamniotic twins is considerably lower than in previous decades, but it is still high and occurs throughout pregnancy.


© 2009 by The American College of Obstetricians and Gynecologists.



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