To estimate if membrane sweeping increases the rate of prelabor rupture of membranes.
This randomized trial of term, uncomplicated pregnancies included 300 patients. Patients were randomly assigned into sweep or no-sweep groups, with patients and delivering providers blinded to group allocation. Only the examining provider in the clinic was unblinded to group allocation. Membranes were then swept or not swept at each weekly visit from 38 weeks of gestation onward, depending on the randomization. Data collected included parity, cervix examination at each visit, estimated gestational age at delivery, rupture of membranes, and maternal or fetal complications.
A total of 162 patients were randomly assigned to the membrane sweep group and 138 to the no-sweep group. There was no difference in baseline characteristics or obstetric and neonatal outcomes between the groups. The average gestational age at delivery and induction rate were not different. The overall prelabor rupture of membranes rate was not significantly higher in the membrane sweep group (12% compared with 7%) (P=.19); however, patients with a cervix more than 1 cm dilated at time of membrane sweeping were more likely to have prelabor rupture of membranes if they were in the membrane sweep group (9.1% compared with 0%; relative risk 1.10, 95% confidence interval 1.03–1.18).
No benefit in gestational age at delivery or reduction of postmaturity occurred from membrane sweeping. Although the overall prelabor rupture of membranes rates were similar, patients with membrane sweeping occurring at more than 1 cm cervical dilation may be at increased risk of prelabor rupture of membranes.
ClinicalTrials.gov, www.clinicaltrials.gov, NCT00294242
Membrane sweeping does not increase the overall rate of prelabor rupture of membranes.
From the 1Tripler Army Medical Center, Honolulu, Hawaii; 2Madigan Army Medical Center, Tacoma, Washington; and 3Mid-South Perinatal Associates, Jackson, Tennessee.
Supported by the Department of Clinical Investigation at Tripler Army Medical Center, Honolulu, Hawaii.
Presented at the 2007 Armed Forces District Annual Meeting, Louisville, Kentucky, October 28–31, 2007, and at the Annual Clinical Meeting of the American College of Obstetricians and Gynecologists as the Donald F. Richardson Memorial Prize Paper, New Orleans, Louisiana, May 3–7, 2008.
The views expressed in this manuscript are those of the authors and do not reflect the official policy or position of the Department of the Army, Department of Defense, or the U.S. Government.
Corresponding author: Micah J. Hill, DO, Blanchfield Army Community Hospital, 650 Joel Drive, Fort Campbell, KY 42223; e-mail: email@example.com.
Financial Disclosure The authors have no potential conflicts of interest to disclose.